From Wenatchee, drive north on Hwy 97 for 40 miles to the town of Chelan.
Board the Lady of the Lake II at Chelan or Fields Point in the morning for the trip up Lake Chelan, then disembark at the tiny port of Lucerne (a dock and a handful of cabins) around lunchtime. The Lady of the Lake II leaves Chelan at 8:30 a.m. and Fields Point at 9:45 a.m. each day through Oct. 31, arriving at Lucerne around 11:45 a.m. From Nov. 2 through April 30 boat service is provided by the Lady Express, which leaves Chelan at 10 a.m. and arrives at Lucerne at noon. Roundtrip fare is $19 per person.
The trail: Starts amid a confusion of dirt roads and trails by the Lucerne dock. Follow signs to Domke Lake Trail 1280. Domke Lake, elevation 2,200 feet, is about 3.5 miles by trail from Lucerne, with a 1,100-foot elevation gain. The grade is steep at first, but levels out into a series of ups and downs after about 1.5 miles. If the camground should be full (unlikely), there are other campsites scattered around the lake.